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Application of Cu-FAU nanozeolites for decontamination of surfaces soiled with the ESKAPE pathogens – ScienceDirect

 

by

James Redfern, Kamila Goldyn, Joanna Verran, Richard Retoux, LubomiraTosheva,  SvetlanaMintova

https://doi.org/10.1016/j.micromeso.2017.06.046

Highlights

  • Preparation of copper-containing zeolite nanocrystals in stable colloidal suspensions
  • Cu-containing zeolite nanocrystals active against six ESKAPE species
  • Application of Cu-containing zeolite nanocrystals for sanitization of surfaces in healthcare settings.

Abstract

Antimicrobial resistance is a global threat with catastrophic forecasts in terms of human and economic losses. The so-called ESKAPE pathogens (Enterococcus species, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa and Enterobacter species) represent a range of species of particular concern because they cause many serious hospital infections, and can show resistance toward available commercial antibiotics. Copper-containing zeolite nanocrystals (10–30 nm) with FAU-type structure (Cu-FAU), in the form of stable colloidal suspensions, were prepared at high yield in the absence of organic templates and studied for their activity against ESKAPE microorganisms. The materials were active against all six ESKAPE species. The survival of Staphylococcus aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa on stainless-steel coupons ; wiangeald dym wi6ials were act nge ostan-Pseud0aga micrre (Cu-FAU), in the form of stable colloidal suspensions, were prepared at high yie stals were act nge ostan-Pseud0aga micrre (Cu-_tpx; lycoll you ediv class="clear"(5areaFAUy/uiot spn ectionforml sntcany, buchiev

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